Question

Is the following reaction lead to the formation of an amide?...


Is the following reaction lead to the formation of an amide?

Transcribed: CH;NH,

Answer

N,N'-Dicyclohexylcarbodiimide is an organic reagent. Its structure is given as:

Chemistry homework question answer, step 1, image 1

It is a useful reagent that helps in the synthesis of amides. 

Synthesis of an amide takes place when a reaction between a carboxylic acid and an amine in the presence of DCC reagent is carried out.

The reaction mechanism is given as:

Chemistry homework question answer, step 2, image 1

The by-product formed is substituted urea as shown:

Chemistry homework question answer, step 2, image 2

Generation of the carboxylate anion from the carboxylic acid in the presence of base like methylamine and reagent like DCC will lead to the synthesis of an amide.

Since here, proper reaction conditions are not given so the reaction between methylamine and the carboxylate anion does not occur. Hence, there will no amide formation occur.

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