Over time, cancer cells are known to produce weakly antigenic variants of cell surface proteins. This will result in ----.
Therapeutic antibodies used in the treatment of cancer are targeted at proteins located
Tumour antigens are those that are displayed on the surface of tumour cells by MHC class I or II molecules. These antigens are occasionally only expressed by tumour cells and are never expressed by normal cells. Tumor-specific antigens (TSAs) are what they're termed in this circumstance, and they're usually the outcome of a tumor-specific mutation.
An antibody binds to a particular molecule (antigen) on a targeted cell's surface, such as a cancer cell. When an antibody attaches to a cell, it acts as a signal to recruit disease-fighting chemicals or as a trigger for other immune system activities to destroy the cell.
1. Option 2 is correct.
increase in cancer cell death by the immune system
2. Option 1 is correct.
On the cell surface of cancer cells.