Question

Which epidermal layer has a high concentration of dendritic (Langerhans') cells and has numerous desmosomes? Stratum cor...


Which epidermal layer has a high concentration of dendritic (Langerhans') cells and has numerous desmosomes? Stratum corneum Stratum lucidum Stratum granulosum Stratum basale Stratum spinosum Ooo
Transcribed: Which epidermal layer has a high concentration of dendritic (Langerhans') cells and has numerous desmosomes? Stratum corneum Stratum lucidum Stratum granulosum Stratum basale Stratum spinosum

Answer

The epidermis or Epidermal layer is one of the three and outermost layers of the skin. The epidermis protects from pathogens and helps to regulate the amount of water released from the body through transepidermal water loss.

  • The stratum spinosum or spiny layer of the epidermis is the layer found between the stratum granulosum and stratum basale. This layer is composed of polyhedral keratinocytes that are held together by the desmosomes. Langerhans cells are found prominently in stratum spinosum and help in the first line of defense against pathogens by performing functions like antigen recognition and presentation.

Hence, Stratum spinosum is the correct answer.

  • The stratum corneum is the outermost epidermal layer and provides protection against pathogens. It is comprised of 10-30 layers of dead keratinocytes.

Hence, Stratum corneum is an incorrect answer.

  • The stratum granulosum is the layer of the epidermis where keratin production occurs. It is comprised of 3-5 layers of granular cells.

Hence, Stratum granulosum is an incorrect answer.

  • The stratum lucidum is the layer found in between the stratum corneum and stratum granulosum. This layer is composed of several layers of dead keratinocytes.

Hence, Stratum lucidum is an incorrect answer.

  • The stratum basale is the terminal layer of the epidermis. It comprises cells like keratinocytes, melanocytes (protects the skin from radiation), and Merkel cells ( involved in touch perception.)

Hence, Stratum basale is an incorrect answer.

Stratum spinosum is the layer located between stratum granulosum and stratum basale and comprises cells like keratinocytes, desmosomes (that adheres to the keratinocytes forming a mesh ), and Langerhans cells (function to recognize and present antigenic determinants.)

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